An α2-AR agonist
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ST 91

Item No. 43562

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-(2,6-diethylphenyl)-4,5-dihydro-1H-imidazol-2-amine, monohydrochloride
CAS Number
4749-61-5
Molecular Formula
C13H19N3 • HCl
Formula Weight
253.8
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥10 mg/mlEthanol: Soluble: ≥10 mg/mlPBS (pH 7.2): Soluble: ≥10 mg/ml
SMILES
CCC1=C(C(CC)=CC=C1)NC2=NCCN2.Cl
InChi Code
InChI=1S/C13H19N3.ClH/c1-3-10-6-5-7-11(4-2)12(10)16-13-14-8-9-15-13;/h5-7H,3-4,8-9H2,1-2H3,(H2,14,15,16);1H
InChi Key
ZLRWFGBEDNTMEU-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    5 mg

    $87

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    10 mg

    $139

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    25 mg

    $326

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    50 mg

    $566

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    Product Description

    ST 91 is an agonist of α2-adrenergic receptors (α2-ARs).1 It induces cAMP accumulation in HEK293 cells expressing α2A-, α2B-, or α2C-ARs (EC50s = 155, 371, and 851 nM, respectively). ST 91 (100 nM) inhibits isoproterenol-induced relaxation in phenylephrine-precontracted isolated rat mesenteric arterial rings.2 Intrathecal administration of ST 91 (10 and 30 µg/animal) reduces paw flinching in the first and second phases of the formalin test in rats.3 It increases plasma atrial natriuretic peptide (ANP) levels, urinary output, and sodium, potassium, and cGMP excretion in conscious rats when administered at a dose of 250 µg/animal.4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

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