An oxidized derivative of epinephrine
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Adrenalone (hydrochloride)

Item No. 43563

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-(3,4-dihydroxyphenyl)-2-(methylamino)-ethanone, monohydrochloride
CAS Number
62-13-5
Molecular Formula
C9H11NO3 • HCl
Formula Weight
217.7
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥ 10 mg/ml
SMILES
O=C(CNC)C1=CC=C(C(O)=C1)O.Cl
InChi Code
InChI=1S/C9H11NO3.ClH/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;/h2-4,10-12H,5H2,1H3;1H
InChi Key
CSRRBDMYOUQTCO-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 g

    $54

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    5 g

    $257

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    Product Description

    Adrenalone is an oxidized derivative of epinephrine.1 It induces dsDNA breaks in RFL-6 rat fetal lung fibroblasts when used at a concentration of 250 µM. Adrenalone (20 mg/kg) increases the blood levels of fibrinogen in rats.2 Formulations containing adrenalone have previously been used as topical agents to prolong the activity of anesthetics.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Murakami, H., Yamada, K., Shirahata, S., et al. Double strand breakage of chromatin DNA in cultured mammalian cells and DNA extracted from λ phage by aromatic reductones derived from adrenalone. Agric. Biol. Chem. 42(5), 1019-1023 (1978).

    2. Henriques, S.B., Henriques, O.B., and Levy, A. Slow hyperfibrinogenaemic action of adrenaline and related substances. Br. J. Pharmacol. Chemother. 11(2), 99-103 (1956).