A nucleoside building block
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N6-Bz-5’-O-DMTr-3’-O-Methyladenosine-2’-O-CED Phosphoramidite

Item No. 43603

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphor amidite], N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-3′-O-methyl-adenosine
CAS Number
179479-02-8
Molecular Formula
C48H54N7O8P
Formula Weight
888.0
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Sparingly soluble: 1-10 mg/ml
SMILES
COC(C=C1)=CC=C1C(C2=CC=C(OC)C=C2)(C3=CC=CC=C3)OC[C@@H]4[C@@H](OC)[C@@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@H](N5C=NC6=C(NC(C7=CC=CC=C7)=O)N=CN=C65)O4
InChi Code
InChI=1S/C48H54N7O8P/c1-32(2)55(33(3)4)64(61-28-14-27-49)63-43-42(59-7)40(62-47(43)54-31-52-41-44(50-30-51-45(41)54)53-46(56)34-15-10-8-11-16-34)29-60-48(35-17-12-9-13-18-35,36-19-23-38(57-5)24-20-36)37-21-25-39(58-6)26-22-37/h8-13,15-26,30-33,40,42-43,47H,14,28-29H2,1-7H3,(H,50,51,53,56)/t40-,42-,43-,47-,64?/m1/s1
InChi Key
FVQVZAFXDJSVIC-PSVHYZMASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    25 mg

    $219

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    50 mg

    $416

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    100 mg

    $657

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    Product Description

    N6-Bz-5'-O-DMTr-3'-O-Methyladenosine-2'-O-CED phosphoramidite is a nucleoside building block that has been used in the synthesis of RNase L agonists.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Morita, K., Kaneko, M., Obika, S., et al. Biologically stable 2-5A analogues containing 3'-O,4'-C-bridged adenosine as potent RNase L agonists. ChemMedChem 2(12), 1703-1707 (2007).