An immunogenic T helper cell epitope
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TET 830-modified T Helper Cell Epitope from Tetanus Toxin (trifluoroacetate salt)

Item No. 43815

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
L-alanyl-L-glutaminyl-L-tyrosyl-L-isoleucyl-L-lysyl-L-alanyl-L-asparaginyl-L-seryl-L-lysyl-L-phenylalanyl-L-isoleucylglycyl-L-isoleucyl-L-threonyl-L-α-glutamyl-L-leucine, trifluoroacetate salt
Molecular Formula
C83H134N20O24 • XCF3COOH
Formula Weight
1796.1
Purity
≥95%
Formulation (Request formulation change)
A solid
Peptide Sequence
AQYIKANSKFIGITEL-OH
Solubility(Learn about Variance in Solubility)
Water: Slightly soluble: 0.1-1 mg/ml
SMILES
C[C@@H](C(N[C@@H](CCC(N[H])=O)C(N[C@@H](CC1=CC=C(O[H])C=C1)C(N[C@@](C(N[C@@H](CCCCN[H])C(N[C@H](C(N[C@@H](CC(N[H])=O)C(N[C@@H](CO[H])C(N[C@@H](CCCCN[H])C(N[C@H](C(N[C@@](C(NCC(N[C@@](C(N[C@]([C@H](O[H])C)([H])C(N[C@@H](CCC(O)=O)C(N[C@H](C(O)=O)CC(C)C)=O)=O)=O)([H])[C@@H](C)CC)=O)=O)([H])[C@@H](C)CC)=O)CC2=CC=CC=C2)=O)=O)=O)=O)C)=O)=O)([H])[C@@H](C)CC)=O)=O)=O)N[H].OC(C(F)(F)F)=O
InChi Code
InChI=1S/C83H134N20O24.C2HF3O2/c1-12-43(6)65(79(122)89-40-63(109)100-66(44(7)13-2)81(124)103-68(48(11)105)82(125)94-55(31-33-64(110)111)74(117)98-59(83(126)127)36-42(4)5)101-76(119)56(37-49-22-16-15-17-23-49)96-72(115)53(25-19-21-35-85)92-78(121)60(41-104)99-75(118)58(39-62(88)108)95-70(113)47(10)90-71(114)52(24-18-20-34-84)93-80(123)67(45(8)14-3)102-77(120)57(38-50-26-28-51(106)29-27-50)97-73(116)54(30-32-61(87)107)91-69(112)46(9)86;3-2(4,5)1(6)7/h15-17,22-23,26-29,42-48,52-60,65-68,104-106H,12-14,18-21,24-25,30-41,84-86H2,1-11H3,(H2,87,107)(H2,88,108)(H,89,122)(H,90,114)(H,91,112)(H,92,121)(H,93,123)(H,94,125)(H,95,113)(H,96,115)(H,97,116)(H,98,117)(H,99,118)(H,100,109)(H,101,119)(H,102,120)(H,103,124)(H,110,111)(H,126,127);(H,6,7)/t43-,44-,45-,46-,47-,48+,52-,53-,54-,55-,56-,57-,58-,59-,60-,65-,66-,67-,68-;/m0./s1
InChi Key
RARBOMOALSFERV-SCGVXIKRSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    TET 830-modified T helper cell epitope from tetanus toxin is an immunogenic T helper (Th) cell epitope derived from the tetanus toxin helper peptide.1 It increases serum levels of IgG, IgA, IL-4, and IFN-γ in combination with self-amplifying RNA lipid nanoparticles (saLNPs) in a mouse model of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection when administered as an adjuvant.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Keikha, R., and Jebali, A. The effect of a peptide adjuvant (YLQPRTFLL) on immune response against SARS-CoV-2 in Balb/C mice when vaccinated with saRNA LNPs. Appl. Biosci. (2025).