An N-terminal peptide fragment of ACTH
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

ACTH (1-4) (trifluoroacetate salt)

Item No. 43818

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
L-seryl-L-tyrosyl-L-seryl-L-methionine
Synonyms
  • Adrenocorticotropic hormone (1-4)
  • Corticotropin (1-4)
  • Ser-Tyr-Ser-Met-OH
Molecular Formula
C20H30N4O8S • XCF3COOH
Formula Weight
486.5
Purity
≥98%
Formulation (Request formulation change)
A solid
Peptide Sequence
SYSM-OH
Solubility(Learn about Variance in Solubility)
Acetonitrile: Slightly soluble: 0.1-1 mg/mlWater: Slightly soluble: 0.1-1 mg/ml
SMILES
[H]N[C@@H](CO)C(N[C@H](C(N[C@@H](CO)C(N[C@H](C(O)=O)CCSC)=O)=O)CC1=CC=C(O)C=C1)=O
InChi Code
InChI=1S/C20H30N4O8S/c1-33-7-6-14(20(31)32)22-19(30)16(10-26)24-18(29)15(23-17(28)13(21)9-25)8-11-2-4-12(27)5-3-11/h2-5,13-16,25-27H,6-10,21H2,1H3,(H,22,30)(H,23,28)(H,24,29)(H,31,32)/t13-,14-,15-,16-/m0/s1
InChi Key
GTYVWTFUSMUWHM-VGWMRTNUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $90

    Add

    5 mg

    $357

    Add

    10 mg

    $580

    Add
    Product Description

    ACTH (1-4) is an N-terminal peptide fragment of adrenocorticotropic hormone (ACTH; Item No. 24257).1 It potentiates natriuresis induced by arginine vasopressin (argipressin; Item No. 24154) in cats when administered at a dose of 20 nmol/kg. Intracerebroventricular administration of ACTH (1-4) (3 µg/animal) potentiates excessive grooming induced by α-melanocyte-stimulating hormone (α-MSH; Item No. 29923) in rats.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Cort, J.H., Cort, J., Nováková, J., et al. Interaction of vasopressins and linear N-terminal ACTH fragments in the induction of natriuresis. Eur. J. Clin. Invest. 4(5), 293-298 (1974).

    2. De Graan, P.N.E., Spruijt, B.M., Eberle, A.N., et al. ACTH1-4 potentiates α-MSH-induced melanophore dispersion and excessive grooming. Peptides 7(1), 1-4 (1986).