An insect neuropeptide
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Product Type

Biochemicals
Peptides
Neuropeptides

Research Area

Neuroscience
Neuroendocrinology

Allatostatin I (trifluoroacetate salt)

Item No. 43824

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
L-alanyl-L-prolyl-L-serylglycyl-L-alanyl-L-glutaminyl-L-arginyl-L-leucyl-L-tyrosylglycyl-L-phenylalanylglycyl-L-leucinamide, trifluoroacetate salt
Molecular Formula
C61H94N18O16 • XCF3COOH
Formula Weight
1335.5
Purity
≥98%
Formulation (Request formulation change)
A solid
Peptide Sequence
APSGAQRLYGFGL-NH2
Solubility(Learn about Variance in Solubility)
Acetonitrile:Water (1:1): Slightly soluble: 0.1-1 mg/mlDMSO: Slightly soluble: 0.1-1 mg/ml
SMILES
[H]N[C@H](C(N1CCC[C@H]1C(N[C@@H](CO)C(NCC(N[C@H](C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@H](C(NCC(N[C@H](C(NCC(N[C@@H](CC(C)C)C(N)=O)=O)=O)CC2=CC=CC=C2)=O)=O)CC3=CC=C(O)C=C3)=O)=O)=O)=O)C)=O)=O)=O)=O)C.O=C(O)C(F)(F)F
InChi Code
InChI=1S/C61H94N18O16.C2HF3O2/c1-32(2)24-41(51(64)86)72-49(84)29-68-53(88)43(26-36-12-8-7-9-13-36)73-50(85)30-69-54(89)44(27-37-16-18-38(81)19-17-37)77-58(93)42(25-33(3)4)76-56(91)39(14-10-22-67-61(65)66)75-57(92)40(20-21-47(63)82)74-52(87)35(6)71-48(83)28-70-55(90)45(31-80)78-59(94)46-15-11-23-79(46)60(95)34(5)62;3-2(4,5)1(6)7/h7-9,12-13,16-19,32-35,39-46,80-81H,10-11,14-15,20-31,62H2,1-6H3,(H2,63,82)(H2,64,86)(H,68,88)(H,69,89)(H,70,90)(H,71,83)(H,72,84)(H,73,85)(H,74,87)(H,75,92)(H,76,91)(H,77,93)(H,78,94)(H4,65,66,67);(H,6,7)/t34-,35-,39-,40-,41-,42-,43-,44-,45-,46-;/m0./s1
InChi Key
FPQQKXZOGCSGEH-DUSDMSLWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $54

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    5 mg

    $175

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    10 mg

    $270

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    Product Description

    Allatostatin I is an insect neuropeptide.1 It is found primarily in the insect corpora allata, which are endocrine glands involved in juvenile hormone biosynthesis. Allatostatin I inhibits juvenile hormone biosynthesis in female cockroaches (D. punctata) at a variety of life stages.2 It reduces hindgut motility, but not juvenile hormone production, in 2-day-old ring-legged earwigs (E. annulipes).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Rankin, S.M., Stay, B., Chan, K., et al. Cockroach allatostatin-immunoreactive neurons and effects of cockroach allatostatin in earwigs. Arch. Insect Biochem. Physiol. 38(4), 155-165 (1998).

    2. Pratt, G.E., Farnsworth, D.E., and Feyerisen, R. Changes in the sensitivity of adult cockroach corpora allata to a brain allatostatin. Mol. Cell. Endocrinol. 70(2), 185-195 (1990).