A metal chelator
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CB-Cyclam

Item No. 43825

Technical Information
Formal Name
1,4,8,11-tetraazabicyclo[6.6.2]hexadecane
CAS Number
130701-19-8
Synonyms
  • Cross-bridged Cyclam
Molecular Formula
C12H26N4
Formula Weight
Purity
≥95%
A solid
DMSO: Sparingly soluble: 1-10 mg/mlEthanol: Soluble: ≥10 mg/mlPBS (pH 7.2): Soluble: ≥10 mg/ml
SMILES
N12CCNCCCN(CCNCCC2)CC1
InChi Code
InChI=1S/C12H26N4/c1-3-13-5-10-16-8-2-4-14-6-9-15(7-1)11-12-16/h13-14H,1-12H2
InChi Key
OBBKVQRWBGOVCF-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    CB-cyclam is a metal chelator.1 It has also been used in the synthesis of bifunctional chelators for copper radioisotopes.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lelong, E., Suh, J.-M., Kim, G., et alComplexation of C-functionalized cyclams with copper(II) and zinc(II): Similarities and changes when compared to parent cyclam analogues. Inorg. Chem. 60(15), 10857-10872 (2021).

    2. Urbanovský, P., David, T., Hlinová, V., et alCross-bridged cyclam derivatives with bis(phosphinate) and phosphinate-phosphonate pendant arms (cb-BPC) as chelators for copper radioisotopes. Org. Biomol. Chem. 23(3), 699-720 (2025).