A metal chelator
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DiAmSar

Item No. 43826

Technical Information
Formal Name
3,6,10,13,16,19-hexaazabicyclo[6.6.6]eicosane-1,8-diamine
CAS Number
91002-72-1
Synonyms
  • Diaminosarcophagine
  • (NH2)2-Sar
Molecular Formula
C14H34N8
Formula Weight
Purity
≥95%
A solid
DMSO: Soluble: ≥10 mg/mlEthanol: Soluble: ≥10 mg/mlPBS (pH 7.2): Soluble: ≥10 mg/ml
SMILES
NC12CNCCNCC(CNCCNC1)(CNCCNC2)N
InChi Code
InChI=1S/C14H34N8/c15-13-7-17-1-2-18-8-14(16,11-21-5-3-19-9-13)12-22-6-4-20-10-13/h17-22H,1-12,15-16H2
InChi Key
UQQQAKFVWNQYTP-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    DiAmSar is a metal chelator.1,2 It has been conjugated to various tumor-targeting ligands and complexed with the copper radioisotope 64Cu for PET imaging in vivo.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wei, L., Ye, Y., Wadas, T.J., et al64Cu-labeled CB-TE2A and diamsar-conjugated RGD peptide analogs for targeting angiogenesis: comparison of their biological activity. Nucl. Med. Biol. 36(3), 277-285 (2009).

    2. Huang, C.-W., Li, Z., Cai, H., et alBiological stability evaluation of the α2β1 receptor imaging agents: Diamsar and DOTA conjugated DGEA peptide. Bioconjug. Chem. 22(2), 256-263 (2011).