An endogenous polyamine
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Putrescine

Item No. 43878

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
CAS Number
110-60-1
Synonyms
  • 1,4-Butanediamine
  • 1,4-Diaminobutane
  • NSC 60545
Molecular Formula
C4H12N2
Formula Weight
88.2
Purity
≥95%
Formulation (Request formulation change)
A semi-solid
Solubility(Learn about Variance in Solubility)
Methanol: Slightly soluble: 0.1-1 mg/mlWater: Sparingly soluble: 1-10 mg/ml
SMILES
NCCCCN
InChi Code
InChI=1S/C4H12N2/c5-3-1-2-4-6/h1-6H2
InChi Key
KIDHWZJUCRJVML-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 g

    $63

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    5 g

    $299

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    10 g

    $565

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    Product Description

    Putrescine is an endogenous polyamine.1,2,3 It is formed through the catabolism of arginine via an ornithine intermediate.2 Levels of putrescine are increased in the cerebrospinal fluid (CSF) of patients with Parkinson’s disease. Plasma levels and bone levels of putrescine are decreased in patients with osteoarthritis and osteoporosis, respectively.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bienz, S., Detterbeck, R., Ensch, C., et al. Putrescine, spermidine, spermine, and related polyamine alkaloids. Alkaloids Chem. Biol. 58, 83-338 (2002).

    2. Jimenez Gutierrez, G.E., Borbolla Jiménez, F.V., Muñoz, L.G., et al. The molecular role of polyamines in age-related diseases: An update. Int. J. Mol. Sci. 24(22), 16469 (2023).

    3. Kara, D.A., Borzova, V.A., Roman, S.G., et al. Polyamines putrescine and spermidine as modulators of protein aggregation rate: The effect on DTT-induced aggregation of α-lactalbumin. Biochimie 227(Pt A), 182-192 (2024).