A heterocycle that has been used as a cofactor in crystallography studies
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2-(1H-Pyrazol-3-yl)pyridine-4-carboxylic Acid (hydrochloride)

Item No. 43958

Technical Information
Formal Name
2-(1H-pyrazol-3-yl)-4-pyridinecarboxylic acid, monohydrochloride
CAS Number
2749892-97-3
Molecular Formula
C9H7N3O2 • HCl
Formula Weight
Purity
≥95%
A solid
DMSO: Sparingly soluble: 1-10 mg/mlEthanol: Slightly soluble: 0.1-1 mg/ml
SMILES
O=C(C1=CC=NC(C2=NNC=C2)=C1)O.Cl
InChi Code
InChI=1S/C9H7N3O2.ClH/c13-9(14)6-1-3-10-8(5-6)7-2-4-11-12-7;/h1-5H,(H,11,12)(H,13,14);1H
InChi Key
JAMNXDHECXBAPS-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    2-(1H-Pyrazol-3-yl)pyridine-4-carboxylic acid is a heterocycle that has been used as a cofactor in crystallography studies of lysine-specific demethylase 4A (KDM4A), also known as Jumanji domain containing 2A (JMJD2A).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Giri, N.C., Passantino, L., Sun, H., et alStructural investigations of the nickel-induced inhibition of truncated constructs of the JMJD2 family of histone demethylases using X-ray absorption spectroscopy. Biochemistry 52(24), 4168-4183 (2013).