A clickable form of UNO peptide
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Azide-UNO Peptide

Item No. 43998

Product Insert (PDF)
Technical Information
Formal Name
(S)-2-((S)-2-((S)-2-((S)-2-(2-((S)-1-((6-((S)-3-(4-(2l4-triaza-1,2-dien-1-yl)phenyl)-2-aminopropanamido)hexanoyl)-L-seryl)pyrrolidine-2-carboxamido)acetamido)propanamido)-6-aminohexanamido)-3-methylbutanamido)-5-guanidinopentanimidic acid
Synonyms
  • CD206 Peptide Ligand Azide
Molecular Formula
C45H76N17O10
Formula Weight
1 mg of lyophilized peptide trifluoroacetic acid salt
Peptide Sequence
4-Azido-Phe-Ahx-SPGAKVR
SMILES
O=C(NCCCCCC(N[C@@H](CO)C(N1[C@@H](CCC1)C(NCC(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(O)=N)=O)=O)=O)=O)=O)=O)=O)[C@H](CC2=CC=C(N=[N]=N)C=C2)N
InChi Code
InChI=1S/C45H76N17O10/c1-26(2)37(43(71)57-31(38(48)66)12-9-21-53-45(49)50)59-41(69)32(11-6-7-19-46)58-39(67)27(3)55-36(65)24-54-42(70)34-13-10-22-62(34)44(72)33(25-63)56-35(64)14-5-4-8-20-52-40(68)30(47)23-28-15-17-29(18-16-28)60-61-51/h15-18,26-27,30-34,37,51,63H,4-14,19-25,46-47H2,1-3H3,(H2,48,66)(H,52,68)(H,54,70)(H,55,65)(H,56,64)(H,57,71)(H,58,67)(H,59,69)(H4,49,50,53)/t27-,30-,31-,32-,33-,34-,37-/m0/s1
InChi Key
FLHDLVYLWAHCLO-KBTJZILRSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    Azide-UNO peptide is a clickable form of UNO peptide, a peptide that binds CD206 on tumor-associated macrophages (TAMs).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lepland, A., Peranzoni, E., Haljasorg, U., et alPeptide-drug conjugate for therapeutic reprogramming of tumor-associated macrophages in breast cancer. Adv. Sci. (Weinh) 12(10), e2410288 (2025).