A positive modulator of IFNAR
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

IFN-α Receptor Recognition Peptide 1 (trifluoroacetate salt)

Item No. 44045

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
L-cysteinyl-L-leucyl-L-lysyl-L-α-aspartyl-L-arginyl-L-histidyl-L-aspartic acid, trifluoroacetate salt
Synonyms
  • Cys-Leu-Lys-Asp-Arg-His-Asp-OH
  • IFN-α (52-58) (human)
  • IFNAR Recognition Peptide 1
  • IRRP1
Molecular Formula
C35H59N13O12S • XCF3COOH
Formula Weight
886.0
Purity
≥95%
Formulation (Request formulation change)
A solid
Peptide Sequence
CLKDRHD-OH
Solubility(Learn about Variance in Solubility)
Water: Slightly soluble: 0.1-1 mg/ml
SMILES
SC[C@H](N)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@H](C(O)=O)CC(O)=O)=O)CC1=CN=CN1)=O)=O)=O)=O)=O.O=C(O)C(F)(F)F
InChi Code
InChI=1S/C35H59N13O12S.C2HF3O2/c1-17(2)10-22(45-28(53)19(37)15-61)31(56)43-20(6-3-4-8-36)29(54)47-24(12-26(49)50)33(58)44-21(7-5-9-41-35(38)39)30(55)46-23(11-18-14-40-16-42-18)32(57)48-25(34(59)60)13-27(51)52;3-2(4,5)1(6)7/h14,16-17,19-25,61H,3-13,15,36-37H2,1-2H3,(H,40,42)(H,43,56)(H,44,58)(H,45,53)(H,46,55)(H,47,54)(H,48,57)(H,49,50)(H,51,52)(H,59,60)(H4,38,39,41);(H,6,7)/t19-,20-,21-,22-,23-,24-,25-;/m0./s1
InChi Key
UXBGUCMSBIFUNA-RGGMAHEYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $35

    Add

    5 mg

    $166

    Add

    10 mg

    $315

    Add
    Cayman Chemical
    Neutrophil Biology Wall Poster

    Explore how neutrophils shape the immune response in health and disease. This poster highlights neutrophil pathogen defense mechanisms, including phagocytosis, degranulation, and NETosis, as well as neutrophil roles in inflammation and NET-associated pathologies.

    DOWNLOAD NOW
    Product Description

    IFN-α receptor recognition peptide 1 (IRRP1) is a peptide that corresponds to amino acids 52-58 of full-length IFN-α and is a positive modulator of IFN-α/β receptor 1 (IFNAR).1 It increases the binding capacity of Daudi cells for IFN-α2. IRRP1 (1 µg/ml) enhances the antiproliferative effect of IFN-α in T98G glial cells and enhances the antiviral effect of IFN-α in encephalomyocarditis virus-infected T98G cells.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Fish, E.N. Interferon receptor recognition peptides enhance the biological potency of interferon alphas. FEBS Lett. 365(1), 87-91 (1995).