An Analytical Reference Standard
Features
  • This product has been formulated as an exempt preparation which meets criteria established by the US DEA
  • Possession of a DEA Controlled Substance registration is not necessary nor is a DEA 222 form required to purchase this product
  • This product is intended to be used as an analytical reference standard
  • Bulk material is available for academic research at qualified institutions; please contact our sales department for pricing
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

11-hydroxy-9(S)-Hexahydrocannabinol (exempt preparation)

Item No. 44129

Exempt Product (US)
Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • 11-hydroxy-9α-Hexahydrocannabinol
  • 11-hydroxy-9α-HHC
  • 11-hydroxy-9(S)-HHC
Technical Information
Formal Name
[6aR-(6aα,9β,10aβ)]-6a,7,8,9,10,10a-hexahydro-1-hydroxy-6,6-dimethyl-3-pentyl-6H-dibenzo[b,d]pyran-9-methanol
CAS Number
74523-47-0
Molecular Formula
C21H32O3
Formula Weight
332.5
Purity
≥95%
Formulation
A 1 mg/ml solution in acetonitrile
SMILES
CC1(C)[C@@]2([H])[C@](C[C@@H](CO)CC2)([H])C3=C(C=C(CCCCC)C=C3O)O1
InChi Code
InChI=1S/C21H32O3/c1-4-5-6-7-14-11-18(23)20-16-10-15(13-22)8-9-17(16)21(2,3)24-19(20)12-14/h11-12,15-17,22-23H,4-10,13H2,1-3H3/t15-,16+,17+/m0/s1
InChi Key
LXSFNMQURHTPIT-GVDBMIGSSA-N
Origin
Synthetic
Regulatory Information
DEA Exempt Notification
This product is a DEA exempt preparation of a scheduled compound - does not require DEA Controlled Substance registration or DEA 222 form. For alternate sizes please contact sales.
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $367

    Add
    Cayman Chemical
    Cayman Spectral Library

    Our free, searchable, GC-MS spectral database contains 70eV EI mass spectral data of 2,000+ of Cayman’s forensic drug standards.

    DOWNLOAD THE DATABASE
    Product Description

    11-hydroxy-9(S)-Hexahydrocannabinol (exempt preparation) (Item No. 44129) is an analytical reference standard categorized as a phytocannabinoid metabolite.1,2,3,4 11-hydroxy-9(S)-Hexahydrocannabinol is an active metabolite of exo-THC (Item No. 36898 | 41216), 9-hexahydrocannabinol, and Δ9-THC (Item Nos. ISO60157 | 43003 | 42138).1,2,3 It induces generalization to Δ9-THC in drug discrimination tests in rats and pigeons.4 11-hydroxy-9(S)-Hexahydrocannabinol is regulated as a Schedule I compound in the United States. 11-hydroxy-9(S)-Hexahydrocannabinol (exempt preparation) (Item No. 44129) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Harvey, D.J., Gill, E.E., Slater, M., et al. Identification of the in vivo liver metabolites of (−)-Δ7-tetrahydrocannabinol produced by the mouse. Drug Metab. Dispos. 8(6), 439-445 (1980).

    2. Kobidze, G., Sprega, G., Montanari, E., et al. The first LC-MS/MS stereoselective bioanalytical methods to quantitatively detect 9R- and 9S-hexahydrocannabinols and their metabolites in human blood, oral fluid and urine. J. Pharm. Biomed. Anal. 240, 115918 (2024).

    3. Jørgensen, C.F., Rasmussen, B.S., Linnet, K., et al. Evidence of 11-hydroxy-hexahydrocannabinol and 11-nor-9-carboxy-hexahydrocannabinol as Novel Human Metabolites of Δ9-tetrahydrocannabinol. Metabolites 13(12), 1169 (2023).

    4. Järbe, T.U., Hiltunen, A.J., Lander, N., et al. Cannabimimetic activity (Δ1-THC cue) of cannabidiol monomethyl ether and two stereoisomeric hexahydrocannabinols in rats and pigeons. Pharmacol. Biochem. Behav. 25(2), 393-399 (1986).