A carbohydrate
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D-Erythronic Acid (potassium salt)

Item No. 44227

Product Insert (PDF)
Technical Information
Formal Name
(2R,3R)-2,3,4-trihydroxy-butanoic acid, monopotassium salt
CAS Number
88759-55-1
Synonyms
  • D-Erythronate
  • (2R,3R)-2,3,4-Trihydroxybutanoate
Molecular Formula
C4H7O5 • K
Formula Weight
174.2
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Acetonitrile:Water (1:1): Sparingly soluble: 1-10 mg/ml
SMILES
O[C@H]([C@@H](CO)O)C([O-])=O.[K+]
InChi Code
InChI=1S/C4H8O5.K/c5-1-2(6)3(7)4(8)9;/h2-3,5-7H,1H2,(H,8,9);/q;+1/p-1/t2-,3-;/m1./s1
InChi Key
NIBJBHRBFKKLFG-SWLXLVAMSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $28

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    5 mg

    $62

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    10 mg

    $83

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    Product Description

    D-Erythronic acid is a carbohydrate found in aqueous humor, cerebrospinal fluid, and blood.1,2 It is an oxidative product of N-acetyl-D-glucosamine (GlcNAc; Item No. 13136) and an oxidative degradation product of glycated lysine residues in proteins.3,4 D-Erythronic acid levels are increased in the urine of patients with transaldolase (TALDO) deficiency.5

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Harding, J.J., Hassett, P.C., Rixon, K.C., et al. Sugars including erythronic and threonic acids in human aqueous humour. Curr. Eye Res. 19(2), 131-136 (1999).

    2. Hoffmann, G.F., Seppel, C.K., Holmes, B., et al. Quantitative organic acid analysis in cerebrospinal fluid and plasma: Reference values in a pediatric population. J. Chromatogr. 617(1), 1-10 (1993).

    3. Jahn, M., Baynes, J.W., and Spiteller, G. The reaction of hyaluronic acid and its monomers, glucuronic acid and N-acetylglucosamine, with reactive oxygen species. Carbohydr. Res. 321(3-4), 228-234 (1999).

    4. Ahmed, M.U., Thorpe, S.R., and Baynes, J.W. Identification of Nε-carboxymethyllysine as a degradation product of fructoselysine in glycated protein. The Journal of Biological Chemisty 261(11), 4889-4894 (1986).

    5. Engelke, U.F., Zijlstra, F.S., Mochel, F., et al. Mitochondrial involvement and erythronic acid as a novel biomarker in transaldolase deficiency. Biochim. Biophys. Acta 1802(11), 1028-1035 (2010).