A pH-dependent protein labeling dye
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Protonex™ Red 600, SE

Item No. 44340

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formula Weight
953.1
Purity
≥90%
Emission
597 nm
Excitation
576 nm
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: soluble
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $460

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    Product Description

    Protonex™ Red 600, SE is a pH-dependent dye that is intended for use in labeling proteins and antibodies. It can be used in conjunction with additional dyes for multi-labeling purposes. Protonex™ Red 600, SE displays excitation/emission maxima of 576/597 nm, respectively, with high fluorescence intensity in acidic pH environments, such as phagosomes, endosomes, and lysosomes, but only weakly fluoresces in the extracellular environment. After conjugation, it can be used for microscopy and flow cytometry applications. It has been used to label anti-CD146 antibodies for immunodetection of cancer cells.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nollet, M., Stalin, J., Moyon, A., et al. A novel anti-CD146 antibody specifically targets cancer cells by internalizing the molecule. Oncotarget 8(68), 112283-112296 (2017).