A nucleoside building block
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DMTr-LNA-5MeU-3-CED Phosphoramidite

Item No. 44349

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-[2,5-anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-α-L-lyxofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione
CAS Number
206055-75-6
Synonyms
  • DMTr-Locked Nucleic Acid-5MeU-3-CED Phosphoramidite
Molecular Formula
C41H49N4O9P
Formula Weight
772.8
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMSO: Sparingly soluble: 1-10 mg/mlEthanol: Sparingly soluble: 1-10 mg/ml
SMILES
COC1=CC=C(C(C2=CC=C(OC)C=C2)(OC[C@]3(O[C@H]4N5C=C(C(NC5=O)=O)C)CO[C@@]4([C@@H]3OP(N(C(C)C)C(C)C)OCCC#N)[H])C6=CC=CC=C6)C=C1
InChi Code
InChI=1S/C41H49N4O9P/c1-27(2)45(28(3)4)55(52-23-11-22-42)54-36-35-38(44-24-29(5)37(46)43-39(44)47)53-40(36,25-50-35)26-51-41(30-12-9-8-10-13-30,31-14-18-33(48-6)19-15-31)32-16-20-34(49-7)21-17-32/h8-10,12-21,24,27-28,35-36,38H,11,23,25-26H2,1-7H3,(H,43,46,47)/t35-,36+,38-,40-,55?/m1/s1
InChi Key
STPXOEPMLLHUDQ-ZRCIEBSPSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    50 mg

    $39

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    100 mg

    $59

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    250 mg

    $106

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    Product Description

    DMTr-LNA-5MeU-3-CED phosphoramidite is a nucleoside building block that has been used in the synthesis of oligonucleotide-lipid conjugates.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Patwa, A., Salgado, G., Dole, F., et al. Tuning molecular interactions in lipid-oligonucleotides assemblies via locked nucleic acid (LNA)-based lipids. Org. Biomol. Chem. 11(41), 7108-7112 (2013).