HSA (fatty acid free)

Human serum albumin (HSA) is a negative acute phase reactant and the most abundant protein in human plasma.¹ It is involved in many bioactive functions, such as regulation of plasma osmotic pressure, extracellular antioxidant defense, and the binding and transport of various endogenous and exogenous compounds. Serum levels of albumin are decreased in patients with myocardial infarction, malignancy, and renal disease, and hypoalbuminemia is associated with morbidity and mortality in hospitalized patients.^2,3 Hypoalbuminemia is also associated with death in patients with COVID-19.² Cayman’s HSA (fatty acid free) protein has a fatty acid content of ≤0.01% by GC-MS and can be used for ELISA, functional assay, and Western blot (WB) applications. This product has had endogenous fatty acids removed and is intended for use in studies requiring precise experimental conditions, such as those focused on fatty acid cellular uptake and metabolism. For in vitro use only.

This protein was isolated from human serum, which was tested at the donor level and found negative for HIV 1/2 antibody, HBsAg, HCV antibody, HIV-1 (NAT), and HCV (NAT) by FDA-licensed screening assays. Although these materials have been tested, no known test method can guarantee that products derived from human source materials are free from infectious agents. The safe and responsible handling of this product is the responsibility of the customer. We accept no liability for injury or illness resulting from the use and/or handling of the product. The customer assumes responsibility for the proper disposal of all materials in accordance with federal and state regulations.

WARNING This product is not for human or veterinary use.

1. Fanali, G., di Masi, A., Trezza, V., et al. Human serum albumin: From bench to bedside. Mol. Aspects Med. 33(3), 209-290 (2012).

2. Rabbani, G., and Ahn, S.N. Review: Roles of human serum albumin in prediction, diagnoses and treatment of COVID-19. Int. J. Biol. Macromol. 193(Pt A), 948-955 (2021).

3. Akirov, A., Masri-Iraqi, H., Atamna, A., et al. Low albumin levels are associated with mortality risk in hospitalized patients. Am. J. Med. 130(12), 1465.e1411-1465.e1419 (2017).