A click chemistry building block
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Methyltetrazine-PEG5-NHS ester

Item No. 44734

Product Insert (PDF)
Technical Information
Formal Name
3-[2-[2-[2-[2-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]ethoxy]ethoxy]ethoxy]ethoxy]-propanoic acid, 2,5-dioxo-1-pyrrolidinyl ester
CAS Number
1802907-92-1
Synonyms
  • MTzS
Molecular Formula
C24H31N5O9
Formula Weight
533.5
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Sparingly soluble: 1-10 mg/ml
SMILES
O=C(CCOCCOCCOCCOCCOC1=CC=C(C=C1)C2=NN=C(N=N2)C)ON3C(CCC3=O)=O
InChi Code
InChI=1S/C24H31N5O9/c1-18-25-27-24(28-26-18)19-2-4-20(5-3-19)37-17-16-36-15-14-35-13-12-34-11-10-33-9-8-23(32)38-29-21(30)6-7-22(29)31/h2-5H,6-17H2,1H3
InChi Key
SWSUSQWZOPGVKP-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    5 mg

    $57

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    10 mg

    $108

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    25 mg

    $257

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    Product Description

    Methyltetrazine-PEG5-NHS ester is a click chemistry building block.1 It has been used to induce protein-DNA cross-linking and as a starting material in the synthesis of clickable antibodies.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hayes, O.G., Partridge, B.E., and Mirkin, C.A. Encoding hierarchical assembly pathways of proteins with DNA. Proc. Natl. Acad. Sci. U.S.A. 118(40), e2106808118 (2021).

    2. Komatsu, T., Kyo, E., Ishii, H., et al. Antibody clicking as a strategy to modify antibody functionalities on the surface of targeted cells. J. Am. Chem. Soc. 142(37), 15644-15648 (2020).