A zwitterionic detergent
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Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

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Biochemicals
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CHAPS

Item No. 44746

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N,N-dimethyl-N-(3-sulfopropyl)-3-[[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]-1-propanaminium, inner salt
CAS Number
75621-03-3
Molecular Formula
C32H58N2O7S
Formula Weight
614.9
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): Soluble: ≥ 10 mg/ml
SMILES
O[C@H]1[C@@]2([H])[C@@]3([H])[C@@]([C@]([C@H](C)CCC(NCCC[N+](C)(C)CCCS([O-])(=O)=O)=O)([H])CC3)([C@H](C[C@]2([H])[C@@]4([C@](C[C@@H](CC4)O)([H])C1)C)O)C
InChi Code
InChI=1S/C32H58N2O7S/c1-21(8-11-29(38)33-14-6-15-34(4,5)16-7-17-42(39,40)41)24-9-10-25-30-26(20-28(37)32(24,25)3)31(2)13-12-23(35)18-22(31)19-27(30)36/h21-28,30,35-37H,6-20H2,1-5H3,(H-,33,38,39,40,41)/t21-,22+,23-,24-,25+,26+,27-,28+,30+,31+,32-/m1/s1
InChi Key
UMCMPZBLKLEWAF-BCTGSCMUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 g

    $28

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    10 g

    $36

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    25 g

    $84

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    Product Description

    CHAPS is a zwitterionic detergent that has been used in membrane protein solubilization.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Rodi, P.M., Bocco Gianello, M.D., Corregido, M.C., et al. Comparative study of the interaction of CHAPS and Triton X-100 with the erythrocyte membrane. Biochim Biophys Acta 1838(3), 859-866 (2014).

    2. Kline, T., Park, H., and Meyerson, L.R. CHAPS solubilization of a G-protein sensitive 5-HT1A receptor from bovine hippocampus. Life Sci. 45(21), 1997-2005 (1989).