A reactive probe for the derivatization of primary amines
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3-(2-Furoyl)quinoline-2-carboxaldehyde

Item No. 44747

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-(2-furanylcarbonyl)-2-quinolinecarboxaldehyde
CAS Number
126769-01-5
Synonyms
  • FQCA
Molecular Formula
C15H9NO3
Formula Weight
251.2
Purity
≥95%
Emission
590 nm
Excitation
490 nm
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Water: Slightly soluble: 0.1-1 mg/ml
SMILES
O=CC1=C(C(C2=CC=CO2)=O)C=C3C=CC=CC3=N1
InChi Code
InChI=1S/C15H9NO3/c17-9-13-11(15(18)14-6-3-7-19-14)8-10-4-1-2-5-12(10)16-13/h1-9H
InChi Key
PNCHURHVMDRFTR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $65

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    5 mg

    $276

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    Product Description

    3-(2-Furoyl)quinoline-2-carboxaldehyde is a reactive probe for the derivatization of primary amines.1 3-(2-Furoyl)quinoline-2-carboxaldehyde reacts with primary amines to form fluorescent isoindoles, which display excitation/emission maxima of 490/590 nm, respectively. 3-(2-Furoyl)quinoline-2-carboxaldehyde has been used for protein labeling.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Beale, S.C., Hsieh, Y.-Z., Wiesler, D., et al. Application of 3-(2-furoyl)quinoline-2-carbaldehyde as a fluorogenic reagent for the analysis of primary amines by liquid chromatography with laser-induced fluorescence detection. J. Chromatogr. 499, 579-587 (1990).

    2. Stoyanov, A.V., Ahmadzadeh, H., and Krylov, S.N. Heterogeneity of protein labeling with a fluorogenic reagent, 3-(2-furoyl)quinoline-2-carboxaldehyde. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 780(2), 283-287 (2002).