Stem Cell-derived Neuron Maturation Reagent Kit

The components of this kit, when combined with an appropriate cell culture media, enhance maturation of immature cortical neurons derived from human pluripotent stem cells.¹ Neural organoids, spinal motoneurons, and non-neuronal lineages have also been shown to respond to this cocktail with enhanced maturation.

Each component in this kit is provided separately, and instructions are included to reconstitute these reagents for direct dilution into cell culture media. The kit is intended to supplement up to 1.5 L of culture media when using the indicated concentrations but provides the flexibility to optimize culture conditions to user’s specifications. Prior to use, reagents must be stored as indicated at -20°C.

WARNING This product is not for human or veterinary use.

1. Hergenreder, E., Minotti, A.P., Zorina, Y., et al. Combined small-molecule treatment accelerates maturation of human pluripotent stem cell-derived neurons. Nat. Biotechnol. 42, 1515-1525 (2024).