A diterpene with diverse biological activities
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Radiclonic Acid

Item No. 44992

Technical Information
Formal Name
(2Z,4R)-rel-2-[(2E,4R,6R,8R,10R)-6-(hydroxymethyl)-2,4,8,10-tetramethyl-2-dodecen-1-ylidene]-4-methyl-pentanedioic acid
CAS Number
49620-14-6
Molecular Formula
C23H40O5
Formula Weight
Purity
≥95%
SMILES
O=C(/C(C[C@@H](C(O)=O)C)=C\C(C)=C\[C@H](C[C@H](C[C@H](C[C@H](CC)C)C)CO)C)O
InChi Code
InChI=1S/C23H40O5/c1-7-15(2)8-16(3)10-20(14-24)11-17(4)9-18(5)12-21(23(27)28)13-19(6)22(25)26/h9,12,15-17,19-20,24H,7-8,10-11,13-14H2,1-6H3,(H,25,26)(H,27,28)/b18-9+,21-12-/t15-,16-,17+,19-,20-/m0/s1
InChi Key
NNPPLRJHBQPBAQ-FAKBHOIGSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Radiclonic acid is a diterpene that has been found in Talaromyces species and has diverse biological activities.1,2,3 It is active against methicillin-resistant S. aureus (MRSA; MIC = 3.13 µg/ml).1 Radiclonic acid is cytotoxic to BIU-87 bladder, Eca-109 esophageal, and BEL-7402 liver cancer cells (IC50s = 12.47, 7.7, and 13.75 µM, respectively).2 It stimulates root growth in Chinese cabbage and rice seedlings.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Chu, M.-J., Wu, Q.-Q., Liu, B.-T., et alMarine natural products with anti-MRSA activities: Promising candidates for antibacterial drug discovery. Bioorg. Chem. 167, 109242 (2025).

    2. Niu, S., Xia, M., Chen, M., et alCytotoxic polyketides isolated from the deep-sea-derived fungus Penicillium chrysogenum MCCC 3A00292. Mar. Drugs 17(12), 686 (2019).

    3. Kinnersley, A.M., Scott, T.C.I., Yopp, J.H., et alPromotion of plant growth by polymers of lactic acid. Plant Growth Regul. 9, 137–146 (1990).