A lipophilic fluorescent probe for neuronal tracing
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Neuro-DiO

Item No. 45054

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5-(1,1-dimethylethyl)-2-[3-[5-(1,1-dimethylethyl)-3-octadecyl-2(3H)-benzoxazolylidene]-1-propen-1-yl]-3-octadecyl-benzoxazolium
CAS Number
938222-76-5
Molecular Formula
C61H101N2O2 • CF3O3S
Formula Weight
1043.6
Purity
≥90%
Emission
501 nm
Excitation
483 nm
Formulation (Request formulation change)
A solid
SMILES
CC(C)(C)C1=CC2=C(C=C1)OC(/C=C/C=C3N(CCCCCCCCCCCCCCCCCC)C4=C(C=CC(C(C)(C)C)=C4)O/3)=[N+]2CCCCCCCCCCCCCCCCCC.FC(S(=O)([O-])=O)(F)F
InChi Code
InChI=1S/C61H101N2O2.CHF3O3S/c1-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-39-48-62-54-50-52(60(3,4)5)44-46-56(54)64-58(62)42-41-43-59-63(55-51-53(61(6,7)8)45-47-57(55)65-59)49-40-38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-2;2-1(3,4)8(5,6)7/h41-47,50-51H,9-40,48-49H2,1-8H3;(H,5,6,7)/q+1;/p-1
InChi Key
UMPKUTHKTYJRDV-UHFFFAOYSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

    $25

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    1 mg

    $48

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    Product Description

    Neuro-DiO is a lipophilic carbocyanine probe for neuronal membrane labeling and tracing. It can be used in fixed tissue or in live tissue for acute or longitudinal studies. Neuro-DiO displays excitation/emission maxima of 483/501 nm, respectively. Upon membrane incorporation, neuro-DiO diffuses across the cell surface, enabling the analysis of neuronal morphology, including dendritic arborization and axonal projections, and can be used for both retrograde and anterograde labeling. Neuro-DiO can be used alone or in conjunction with additional probes for multi-labeling applications and in flow cytometric analysis.

    WARNING This product is not for human or veterinary use.