An encephalitogenic peptide
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MOG (92–106) (mouse) (trifluoroacetate salt)

Item No. 45096

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • Myelin Oligodendrocyte Glycoprotein (92-106)
Molecular Formula
C80H105N21O27S • XCF3COOH
Formula Weight
1824.9
Purity
≥95%
Formulation (Request formulation change)
A solid
Peptide Sequence
H-DEGGYTCFFRDHSYQ-NH2
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥10 mg/ml
SMILES
O=C(O)C[C@H](N[H])C(N[C@@H](CCC(O)=O)C(NCC(NCC(N[C@@H](CC1=CC=C(O[H])C=C1)C(N[C@]([C@H](O[H])C)([H])C(N[C@@H](CS[H])C(N[C@H](C(N[C@H](C(N[C@@H](CCC/N=C(N[H])/N)C(N[C@@H](CC(O)=O)C(N[C@@H](CC2=CN([H])C=N2)C(N[C@@H](CO[H])C(N[C@@H](CC3=CC=C(O[H])C=C3)C(N[C@@H](CCC(N[H])=O)C(O)=O)=O)=O)=O)=O)=O)=O)CC4=CC=CC=C4)=O)CC5=CC=CC=C5)=O)=O)=O)=O)=O)=O)=O.O=C(O)C(F)(F)F
InChi Code
InChI=1S/C80H105N21O27S.C2HF3O2/c1-40(103)66(101-75(123)52(29-43-14-18-46(104)19-15-43)90-62(108)36-87-61(107)35-88-68(116)50(23-25-63(109)110)91-67(115)48(81)32-64(111)112)78(126)100-59(38-129)77(125)96-54(28-42-11-6-3-7-12-42)72(120)94-53(27-41-9-4-2-5-10-41)70(118)92-49(13-8-26-86-80(83)84)69(117)98-57(33-65(113)114)74(122)97-56(31-45-34-85-39-89-45)73(121)99-58(37-102)76(124)95-55(30-44-16-20-47(105)21-17-44)71(119)93-51(79(127)128)22-24-60(82)106;3-2(4,5)1(6)7/h2-7,9-12,14-21,34,39-40,48-59,66,102-105,129H,8,13,22-33,35-38,81H2,1H3,(H2,82,106)(H,85,89)(H,87,107)(H,88,116)(H,90,108)(H,91,115)(H,92,118)(H,93,119)(H,94,120)(H,95,124)(H,96,125)(H,97,122)(H,98,117)(H,99,121)(H,100,126)(H,101,123)(H,109,110)(H,111,112)(H,113,114)(H,127,128)(H4,83,84,86);(H,6,7)/t40-,48+,49+,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,66+;/m1./s1
InChi Key
NANSHFOKBMWIOA-XVHTXGAUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $35

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    5 mg

    $158

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    10 mg

    $280

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    25 mg

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    Product Description

    Myelin oligodendrocyte glycoprotein (MOG) (92-106) is an encephalitogenic peptide and a peptide fragment of MOG, a protein involved in demyelinating CNS disorders.1 MOG (92-106) induces relapsing-remitting experimental autoimmune encephalomyelitis (RR-EAE) in SJL/J mice that lack NK1.1+ T cells and express a Th2-low phenotype. It induces a primary progressive (PP) form of EAE when used alone but induces the secondary progressive (SP) form when supplemented with B. pertussis in A.SW mice that have a Th2-responsive phenotype.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Tsunoda, I., Kuang, L.Q., Theil, D.J., et al. Antibody association with a novel model for primary progressive multiple sclerosis: induction of relapsing-remitting and progressive forms of EAE in H2s mouse strains. Brain Pathol. 10(3), 402-418 (2000).