A TEAD4 inhibitor
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LM-41

Item No. 45312

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-([1,1′-biphenyl]-3-ylamino)-4-fluoro-benzoic acid
CAS Number
2996821-30-6
Molecular Formula
C19H14FNO2
Formula Weight
307.3
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥ 10 mg/ml
SMILES
O=C(C1=CC=C(C=C1NC2=CC=CC(C3=CC=CC=C3)=C2)F)O
InChi Code
InChI=1S/C19H14FNO2/c20-15-9-10-17(19(22)23)18(12-15)21-16-8-4-7-14(11-16)13-5-2-1-3-6-13/h1-12,21H,(H,22,23)
InChi Key
JGUSPMKKPPHSQY-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    5 mg

    $215

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    10 mg

    $323

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    25 mg

    $645

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    Cayman Chemical
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    Product Description

    LM-41 is a covalent TEA domain transcription factor 4 (TEAD4) inhibitor.1 It reduces migration of MDA-MB-231 breast cancer cells when used at a concentration of 10 µM.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Fnaiche, A., Mélin, L., Suárez, N.G., et al. Development of LM-41 and AF-2112, two flufenamic acid-derived TEAD inhibitors obtained through the replacement of the trifluoromethyl group by aryl rings. Biooorg. Med. Chem. 95:129488, (2023).