A calcium channel inhibitor
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Pincainide

Item No. 45339

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-(2,6-dimethylphenyl)hexahydro-1H-azepine-1-acetamide
CAS Number
83471-41-4
Synonyms
  • IQB-M-81
Molecular Formula
C16H24N2O
Formula Weight
260.4
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: Slightly soluble: 0.1-1mg/ml
SMILES
CC1=CC=CC(C)=C1NC(CN2CCCCCC2)=O
InChi Code
InChI=1S/C16H24N2O/c1-13-8-7-9-14(2)16(13)17-15(19)12-18-10-5-3-4-6-11-18/h7-9H,3-6,10-12H2,1-2H3,(H,17,19)
InChi Key
RJOUHGWLHPOQSA-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    500 µg

    $99

    Add

    1 mg

    $188

    Add

    5 mg

    $693

    Add

    10 mg

    $891

    Add
    Product Description

    Pincainide is a calcium channel inhibitor.1,2 It reduces norepinephrine-induced calcium influx and increases calcium efflux in isolated rat aortic strips.1 Pincainide reduces phasic and tonic contractions induced by norepinephrine (IC50s = 880 and 780 µM, respectively) and high potassium (IC50s = 620 and 670 µM, respectively) in isolated rat aortic strips. It also decreases heart rate, contractile force, and the maximum following frequency in isolated rat right atria.2 Infiltration of pincainide (1% solution) induces local anesthesia in rabbits with a duration of 240 minutes.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1.  .

    2.  .

    3.  .