An M1 receptor positive allosteric modulator
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M1 mAChR Modulator-1

Item No. 45400

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-fluoro-4-((3-((3R,4S)-3-hydroxytetrahydro-2H-pyran-4-yl)-7,8-dimethyl-4-oxo-3,4-dihydroquinazolin-6-yl)methyl)-N-(2-methoxyethyl)benzamide
CAS Number
2247999-07-9
Molecular Formula
C26H30FN3O5
Formula Weight
483.5
Purity
≥98%
Formulation (Request formulation change)
A solid
SMILES
O=C1C2=CC(CC3=CC(F)=C(C(NCCOC)=O)C=C3)=C(C)C(C)=C2N=CN1[C@H]4CCOC[C@@H]4O
InChi Code
InChI=1S/C26H30FN3O5/c1-15-16(2)24-20(26(33)30(14-29-24)22-6-8-35-13-23(22)31)12-18(15)10-17-4-5-19(21(27)11-17)25(32)28-7-9-34-3/h4-5,11-12,14,22-23,31H,6-10,13H2,1-3H3,(H,28,32)/t22-,23-/m0/s1
InChi Key
SNQCVLJLRXRTTJ-GOTSBHOMSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $99

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    5 mg

    $446

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    10 mg

    $743

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    Product Description

    M1 mAChR modulator-1 is a positive allosteric modulator of M1 muscarinic acetylcholine receptors.1 It increases the number of fecal pellets excreted by male mice and rats when administered orally at 1 mg/kg.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sakai, S., Seto, M., Takami, K., et al. Heterocyclic compounds useful as modulators of acetylcholine receptors. (2018).