An NLRP3 inflammasome inhibitor
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Emlenoflast

Item No. 45477

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)amino]carbonyl]-1-(1-methylethyl)-1H-pyrazole-3-sulfonamide
CAS Number
1995067-59-8
Synonyms
  • Inzomelid
  • IZD-174
  • MCC7840
Molecular Formula
C19H24N4O3S
Formula Weight
388.5
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥ 10 mg/ml
SMILES
O=C(NS(=O)(C1=NN(C(C)C)C=C1)=O)NC2=C3CCCC3=CC4=C2CCC4
InChi Code
InChI=1S/C19H24N4O3S/c1-12(2)23-10-9-17(21-23)27(25,26)22-19(24)20-18-15-7-3-5-13(15)11-14-6-4-8-16(14)18/h9-12H,3-8H2,1-2H3,(H2,20,22,24)
InChi Key
MTOUOUSKXWSTAX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    5 mg

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    Cayman Chemical
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    Product Description

    Emlenoflast is an inhibitor of the NOD-like receptor protein 3 (NLRP3) inflammasome.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Coll, R., Cooper, M., O'Neil, L., et al. Sulfonylureas and related compounds and use of same. WO2016131098, (2016).