A glycosylated depside with antibacterial activity
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Ariestatin A

Item No. 45508

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-hydroxy-4-((2-hydroxy-6-tridecyl-4-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)benzoyl)oxy)-6-methylbenzoic acid
Molecular Formula
C34H48O12
Formula Weight
648.7
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Methanol: Slightly Soluble: 0.1-1 mg/ml
SMILES
OC[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@H](OC2=CC(CCCCCCCCCCCCC)=C(C(OC3=CC(C)=C(C(O)=O)C(O)=C3)=O)C(O)=C2)O1
InChi Code
InChI=1S/C34H48O12/c1-3-4-5-6-7-8-9-10-11-12-13-14-21-16-23(45-34-31(40)30(39)29(38)26(19-35)46-34)18-25(37)28(21)33(43)44-22-15-20(2)27(32(41)42)24(36)17-22/h15-18,26,29-31,34-40H,3-14,19H2,1-2H3,(H,41,42)/t26-,29+,30+,31-,34-/m1/s1
InChi Key
OCISTDVCPBSMGQ-CBOGNJLYSA-N
Origin
Fungus/Austroacremonium gemini
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    250 µg

    $149

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    1 mg

    $536

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    Product Description

    Ariestatin A is a polyketide synthase-derived glycosylated depside that has been found in A. gemini and has antibacterial activity.1 It is active against B. subtilis,S. aureus, and methicillin-resistant S. aureus (MRSA; MICs = 1.6, 3.1, and 6.3 µg/ml, respectively).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sbaraini, N., Crombie, A., Kalaitzis, J.A., et al. The aquastatin biosynthetic gene cluster encodes a versatile polyketide synthase capable of synthesising heteromeric depsides with diverse alkyl side chains. Chem. Sci. 15(45), 18872-18880 (2024).