An ionizable cationic lipid
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

BiP-20

Item No. 45618

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
bis(2-octyldodecyl) (2-(dimethylamino)ethyl)phosphoramidate
Molecular Formula
C44H93N2O3P
Formula Weight
729.2
Purity
≥95%
Formulation (Request formulation change)
A 50 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
Ethanol: Soluble: ≥10 mg/ml
SMILES
CCCCCCCCCCC(CCCCCCCC)COP(NCCN(C)C)(OCC(CCCCCCCC)CCCCCCCCCC)=O
InChi Code
InChI=1S/C44H93N2O3P/c1-7-11-15-19-23-25-29-33-37-43(35-31-27-21-17-13-9-3)41-48-50(47,45-39-40-46(5)6)49-42-44(36-32-28-22-18-14-10-4)38-34-30-26-24-20-16-12-8-2/h43-44H,7-42H2,1-6H3,(H,45,47)
InChi Key
ZNOCWFGZDUJECF-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    5 mg

    $155

    Add

    10 mg

    $295

    Add

    25 mg

    $620

    Add

    50 mg

    $930

    Add
    Cayman Chemical
    Ionizable Lipids – Your Path from R&D to GMP

    Seamlessly bridge your LNP discovery journey from RUO to bulk GLP-tox and GMP excipient-grade material.

    Explore CGMP Lipid Services
    Product Description

    BiP-20 is an ionizable cationic lipid that has been used in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA and single-guide RNA (sgRNA) in vivo.1 LNPs containing BiP-20 are targeted to the liver. BiP-20-containing LNPs encapsulating Cas9 mRNA and transthyretin (TTR) sgRNA decrease serum levels of TTR in mice to a greater extent than LNPs containing LP-01 (Item No. 37278).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Jozić, A., Le Roux, C., Kim, J., et al. In vivo endosomal escape assay identifies mechanisms for efficient hepatic LNP delivery. Nat. Biotechnol. (2026).