A cosmeceutical copper (II)-peptide complex
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Product Categories

Product Type

Biochemicals
Peptides

Research Area

Cell Biology
Cell Death
Apoptosis

Copper Tripeptide-3 (hydrochloride)

Item No. 45777

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
[L-alanyl-κN-L-histidyl-κN,κN3-L-lysinato(2-)]-copper, dihydrochloride
Synonyms
  • ​​AHK-Cu
Molecular Formula
C15H24CuN6O4 • 2HCl
Formula Weight
488.9
Purity
≥90%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): Sparingly soluble: 1-10 mg/ml
SMILES
[O]=C1[C@H](C)[NH2][Cu+2]2[N]3=C[NH]C=C3C[C@@H](C([NH][C@@H](CCCC[NH2])C([O-])=[O])=[O])[N-]21.Cl.Cl
InChi Code
InChI=1S/C15H26N6O4.2ClH.Cu/c1-9(17)13(22)21-12(6-10-7-18-8-19-10)14(23)20-11(15(24)25)4-2-3-5-16;;;/h7-9,11-12H,2-6,16-17H2,1H3,(H4,18,19,20,21,22,23,24,25);2*1H;/q;;;+2/p-2/t9-,11-,12-;;;/m0.../s1
InChi Key
GEQHNUYDVXGREN-ANGBITDVSA-L
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    50 mg

    $29

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    100 mg

    $46

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    250 mg

    $105

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    Product Description

    Copper tripeptide-3 is a cosmeceutical copper (II)-peptide complex.1 It inhibits apoptosis and increases the viability of primary dermal papilla cells (DPCs) at a concentration of 1 nM. Copper tripeptide-3 increases hair follicle length at concentrations of 0.001-1 nM but decreases it at concentrations of 10-100 nM in ex vivo human hair follicles. Formulations containing copper tripeptide-3 have been used in anti-aging cosmetics.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Pyo, H.K., Yoo, H.G., Won, C.H., et al. The effect of tripeptide-copper complex on human hair growth in vitro. Arch. Pharm. Res. 30(7), 834-839 (2007).