A thermolysin and α-glucosidase inhibitor
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CQ

Item No. 45825

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-(4-chlorophenyl)-4(3H)-quinazolinone
CAS Number
7455-77-8
Molecular Formula
C14H9ClN2O
Formula Weight
256.7
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Slightly Soluble: 0.1-1 mg/ml
SMILES
O=C1N=C(C2=CC=C(Cl)C=C2)NC3=C1C=CC=C3
InChi Code
InChI=1S/C14H9ClN2O/c15-10-7-5-9(6-8-10)13-16-12-4-2-1-3-11(12)14(18)17-13/h1-8H,(H,16,17,18)
InChi Key
AKHUKZJZNGHOJU-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $49

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    5 mg

    $221

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    10 mg

    $417

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    25 mg

    $735

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    Product Description

    CQ is an inhibitor of thermolysin and α-glucosidase (IC50s = 1.25 and 12.5 µM, respectively).1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Khan, M.T., Khan, R., Wuxiuer, Y., et al. Identification of novel quinazolin-4(3H)-ones as inhibitors of thermolysin, the prototype of the M4 family of proteinases. Bioorg. Med. Chem. 18(12), 4317-4327 (2010).

    2. Wei, M., Chai, W.M., Wang, R., et al. Quinazolinone derivatives: Synthesis and comparison of inhibitory mechanisms on α-glucosidase. Bioorg. Med. Chem. 25(4), 1303-1308 (2017).