A potential impurity in commercial preparations of eszopiclone
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RP 48497

Item No. 45842

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
6-(5-chloro-2-pyridinyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one
CAS Number
148891-53-6
Molecular Formula
C11H7ClN4O
Formula Weight
246.7
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Slightly soluble: 0.1-1 mg/mlEthanol: Slightly soluble: 0.1-1 mg/ml
SMILES
ClC1=CN=C(N(CC2=NC=CN=C23)C3=O)C=C1
InChi Code
InChI=1S/C11H7ClN4O/c12-7-1-2-9(15-5-7)16-6-8-10(11(16)17)14-4-3-13-8/h1-5H,6H2
InChi Key
ZWMNDASTKOEZHE-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $49

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    10 mg

    $78

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    50 mg

    $343

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    100 mg

    $637

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    Product Description

    RP 48497 is a potential impurity in commercial preparations of the sedative-hypnotic eszopiclone.1 It is a photodegradation product formed by exposure to bright light.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sha, Y., Zhang, L., Du, G.J., et al. Synthesis of RP 48497, an impurity of eszopiclone. Molecules 13(8), 1817-1821 (2008).