An ACE inhibitor
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Dipeptide 2

Item No. 45932

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
L-valyl-L-tryptophan
CAS Number
24587-37-9
Synonyms
  • Dipeptide VW
  • L-Val-L-Trp-OH
  • Valyl-tryptophan
Molecular Formula
C16H21N3O3
Formula Weight
303.4
Purity
≥95%
Formulation (Request formulation change)
A solid
Peptide Sequence
VW-OH
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥10 mg/mlEthanol: Sparingly soluble: 1-10 mg/mlPBS pH 7.2: Sparingly soluble: 1-10 mg/ml
SMILES
CC(C)[C@H](N)C(N[C@H](C(O)=O)CC1=CNC2=CC=CC=C12)=O
InChi Code
InChI=1S/C16H21N3O3/c1-9(2)14(17)15(20)19-13(16(21)22)7-10-8-18-12-6-4-3-5-11(10)12/h3-6,8-9,13-14,18H,7,17H2,1-2H3,(H,19,20)(H,21,22)/t13-,14-/m0/s1
InChi Key
LZDNBBYBDGBADK-KBPBESRZSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 mg

    $25

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    1 g

    $38

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    5 g

    $113

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    Product Description

    Dipeptide 2 is an inhibitor of angiotensin-converting enzyme (ACE; IC50 = 1.4 µM).1 It reduces systolic blood pressure in spontaneously hypertensive rats at 100 mg/kg. Formulations containing dipeptide 2 have been used in cosmetics and skin care products.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Saito, Y., Wanezaki, K., Kawato, A., et al. Antihypertensive effects of peptide in sake and its by-products on spontaneously hypertensive rats. Biosci. Biotechnol. Biochem. 58(5), 812-816 (1994).