A cosmeceutical peptide
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Octapeptide-2

Item No. 45963

Technical Information
Formal Name
L-threonyl-L-alanyl-L-α-glutamyl-L-α-glutamyl-L-histidyl-L-α-glutamyl-L-valyl-L-methionine
CAS Number
1374396-34-5
Synonyms
  • Thr-Ala-Glu-Glu-His-Glu-Val-Met-OH
Molecular Formula
C38H60N10O16S
Formula Weight
Purity
≥98%
A solid
Peptide Sequence
TAEEHEVM-OH
PBS (pH 7.2): Sparingly soluble: 1-10 mg/ml
SMILES
CSCC[C@@H](C(O)=O)NC([C@H](C(C)C)NC([C@H](CCC(O)=O)NC([C@@H](NC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC([C@H](C)NC([C@@H](N)[C@H](O)C)=O)=O)=O)=O)CC1=CN=CN1)=O)=O)=O
InChi Code
InChI=1S/C38H60N10O16S/c1-17(2)30(37(62)46-24(38(63)64)12-13-65-5)48-34(59)23(8-11-28(54)55)45-35(60)25(14-20-15-40-16-41-20)47-33(58)22(7-10-27(52)53)44-32(57)21(6-9-26(50)51)43-31(56)18(3)42-36(61)29(39)19(4)49/h15-19,21-25,29-30,49H,6-14,39H2,1-5H3,(H,40,41)(H,42,61)(H,43,56)(H,44,57)(H,45,60)(H,46,62)(H,47,58)(H,48,59)(H,50,51)(H,52,53)(H,54,55)(H,63,64)/t18-,19+,21-,22-,23-,24-,25-,29-,30-/m0/s1
InChi Key
IZUXSDLDQJZDFW-BNJNSGOPSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Octapeptide-2 is a cosmeceutical peptide.1 It corresponds to the octapeptide sequence at positions 74-81 and 137-144 of the bombinin-like peptides 1 (BLP-1) precursor protein in the skin secretions of B. orientalis.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. He, Q., Liao, Y., Wu, Y., et al. Bioactive oligopeptides and the application in skin regeneration and rejuvenation. J. Appl. Biomater. Funct. Mater. (2025).

    2. Gibson, B.W., Tang, D.Z., Mandrell, R., et al. Bombinin-like peptides with antimicrobial activity from skin secretions of the Asian toad, Bombina orientalis. The Journal of Biological Chemisty 266(34), 23103-23111 (1991).