A labeling reagent
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DBCO-PEG4-TFP ester

Item No. 45967

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • Dibenzocyclooctyne-PEG4-tetrafluorophenyl ester
Molecular Formula
C36H36F4N2O8
Formula Weight
700.7
Purity
≥95%
Formulation (Request formulation change)
A 10 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
DMSO: Sparingly soluble: 1-10 mg/mlEthanol: Soluble: ≥10 mg/mlMethanol: Slightly soluble: 0.1-1 mg/ml
SMILES
O=C(OC1=C(F)C(F)=CC(F)=C1F)CCOCCOCCOCCOCCNC(CCC(N2C3=CC=CC=C3C#CC4=CC=CC=C4C2)=O)=O
InChi Code
InChI=1S/C36H36F4N2O8/c37-28-23-29(38)35(40)36(34(28)39)50-33(45)13-15-46-17-19-48-21-22-49-20-18-47-16-14-41-31(43)11-12-32(44)42-24-27-7-2-1-5-25(27)9-10-26-6-3-4-8-30(26)42/h1-8,23H,11-22,24H2,(H,41,43)
InChi Key
QRXIYJCUEMZLDN-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $25

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    5 mg

    $113

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    10 mg

    $200

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    25 mg

    $438

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    Product Description

    DBCO-PEG4-TFP ester is a labeling reagent containing an amine-reactive tetrafluorophenyl (TFP) ester moiety and an azido-reactive dibenzocyclooctyne (DBCO) copper-free click chemistry moiety connected via a PEG linker. It has been used to conjugate antibodies to metal-chelating polymers for mass cytometry.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Zhang, Y., Liu, P., Majonis, D., et al. Polymeric dipicolylamine based mass tags for mass cytometry. Chem. Sci. 13(11), 3233-3243 (2022).