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Ibogaminalog (hydrochloride)

Item No. 46052

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • DM506
Technical Information
Formal Name
1,2,3,4,5,6-hexahydro-3-methyl-azepino[4,5-b]indole, monohydrochloride
CAS Number
15918-76-0
Molecular Formula
C13H16N2 • HCl
Formula Weight
236.7
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥10 mg/mLEthanol: Sparingly Soluble: 1-10 mg/mL
SMILES
CN(CC1)CCC2=C1NC3=C2C=CC=C3.Cl
InChi Code
InChI=1S/C13H16N2.ClH/c1-15-8-6-11-10-4-2-3-5-12(10)14-13(11)7-9-15;/h2-5,14H,6-9H2,1H3;1H
InChi Key
IMSTUTANZYAQSG-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Ibogaminalog (hydrochloride) (Item No. 46052) is an analytical reference standard categorized as an ibogalog.1 Ibogaminalog induces sedative and anxiolytic-like behavior in stressed and non-stressed mice but does not induce the head-twitch response, indicating a lack of hallucinogenic potential.2 It also reduces neuropathic pain in mice and cue-induced drug-seeking in rats after self-administration of heroin (Item Nos. ISO60187 | 9001543 | 9003076).1,3 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Arias, H.R., Micheli, L., Jensen, A.A., et al. Ibogalogs decrease neuropathic pain in mice through a mechanism involving crosstalk between 5-HT2A and mGlu2 receptors. Biomed. Pharmacother. 184, 117887 (2025).

    2. Arias, H.R., Rudin, D., Hines, D.J., et al. The novel non-hallucinogenic compound DM506 (3-methyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole) induces sedative-and anxiolytic-like activity in mice by a mechanism involving 5-HT2A receptor activation. Eur. J. Pharmacol. 966, 176329 (2024).

    3. Looschen, K., Khatri, S.N., Maulik, M., et al. Novel psychoplastogen DM506 reduces cue-induced heroin-seeking and inhibits tonic GABA currents in the Prelimbic Cortex. Neurochem. Int. 178, 105785 (2024).