A sesquiterpene with antibacterial and anticancer activities
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Bisabolol oxide A

Item No. 46064

Technical Information
Formal Name
(3S,6S)-tetrahydro-2,2,6-trimethyl-6-[(1S)-4-methyl-3-cyclohexen-1-yl]-2H-pyran-3-ol
CAS Number
22567-36-8
Synonyms
  • α-Bisabolol oxide A
Molecular Formula
C15H26O2
Formula Weight
Purity
≥95%
A 10 mg/ml solution in ethanol
SMILES
O[C@H]1CC[C@]([C@@]2(CC=C(CC2)C)[H])(C)OC1(C)C
InChi Code
InChI=1S/C15H26O2/c1-11-5-7-12(8-6-11)15(4)10-9-13(16)14(2,3)17-15/h5,12-13,16H,6-10H2,1-4H3/t12-,13+,15+/m1/s1
InChi Key
WJHRAVIQWFQMKF-IPYPFGDCSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Bisabolol oxide A is an oxygenated sesquiterpene that has been found in M. chamomilla and has antibacterial and anticancer activities.1,2,3 It is active against Gram-positive (MICs = 1.56-3.125 mg/ml) and Gram-negative bacteria (MICs = 3.125 mg/ml for all).2 Liposomal nanoparticles containing bisabolol oxide A induce apoptosis and inhibit the migration of DU145 prostate cancer cells.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lu, J., Jiang, Z., Dang, J., et al. GC-MS combined with fast GC E-Nose for the analysis of volatile components of chamomile (Matricaria chamomilla L.). Foods 13(12), 1865 (2024).

    2. Alimi, D., Hraoui, M., Hajri, A., et al. Bioactivity and molecular docking studies of selected plant compounds. J. Sci. Food Agric. 104(7), 4391-4399 (2024).

    3. Fekri Kohan, S., Arefi Khorrami, Z., Bahrevar Fatideh, F., et al. Anticancer effects of bisabolol oxide A-loaded micellar/liposomal nanoparticles on DU-145 cells with deregulation of miR-34a and miR-181a: In silico and in vitro studies. BMC Biotechnol. 26(1), 107 (2026).