An impurity in commercial preparations of risperidone
Related Products
Isomer(s)
15556Paliperidone
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Risperidone N-oxide

Item No. 46115

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-[2-[cis-4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-oxido-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one
CAS Number
1894509-66-0
Synonyms
  • cis-Risperidone N-oxide
Molecular Formula
C23H27FN4O3
Formula Weight
426.5
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥10 mg/mlEthanol: Soluble: ≥10 mg/ml
SMILES
FC1=CC=C(C([C@@H]2CC[N@+]([O-])(CC2)CCC3=C(C)N=C(CCCC4)N4C3=O)=NO5)C5=C1
InChi Code
InChI=1S/C23H27FN4O3/c1-15-18(23(29)27-10-3-2-4-21(27)25-15)9-13-28(30)11-7-16(8-12-28)22-19-6-5-17(24)14-20(19)31-26-22/h5-6,14,16H,2-4,7-13H2,1H3/t16-,28+
InChi Key
CQQKMRDMDXQQRT-JIBAXXMISA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $35

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    5 mg

    $158

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    10 mg

    $280

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    25 mg

    $525

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    Product Description

    Risperidone N-oxide is a potential impurity found in commercial preparations of the atypical antipsychotic risperidone.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Tomar, R.S., Joseph, T.J., Murthy, A.S., et al. Identification and characterization of major degradation products of risperidone in bulk drug and pharmaceutical dosage forms. J. Pharm. Biomed. Anal. 36(1), 231-235 (2004).

    2. Germann, D., Kurylo, N., and Han, F. Risperidone. Profiles Drug Subst. Excip. Relat. Methodol. 37, 313-361 (2012).