A salicylanilide anthelmintic
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Oxyclozanide

Item No. 46177

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2,3,5-trichloro-N-(3,5-dichloro-2-hydroxyphenyl)-6-benzamide
CAS Number
2277-92-1
Molecular Formula
C13H6Cl5NO3
Formula Weight
401.5
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥10 mg/mlEthanol: Soluble: ≥10 mg/ml
SMILES
ClC1=CC(NC(C2=C(C(Cl)=CC(Cl)=C2Cl)O)=O)=C(O)C(Cl)=C1
InChi Code
InChI=1S/C13H6Cl5NO3/c14-4-1-6(16)11(20)8(2-4)19-13(22)9-10(18)5(15)3-7(17)12(9)21/h1-3,20-21H,(H,19,22)
InChi Key
JYWIYHUXVMAGLG-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    25 mg

    $25

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    50 mg

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    100 mg

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    500 mg

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    Cayman Chemical
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    Product Description

    Oxyclozanide is a salicylanilide anthelmintic.1,2 In vitro, it uncouples oxidative phosphorylation in rat liver mitochondria and increases oxygen uptake and death in sheep river flukes (F. hepatica).1 Oxyclozanide (22.5 mg/kg) decreases the survival of rumen fluke (C. daubneyi) larvae and adult worms by 82 and 95.9%, respectively, in goats.2 Formulations containing oxyclozanide have been used in the treatment of fascioliasis in cattle, sheep, and goats.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Corbett, J.R., and Goose, A.J. The biochemical mode of action of the fasciolicides nitroxynil, hexachlorophane and oxyclozanide. Biochem. J. 121(3), (1971).

    2. Paraud, C., Gaudin, C., Pors, I., et al. Efficacy of oxyclozanide against the rumen fluke Calicophoron daubneyi in experimentally infected goats. Vet. J. 180(2), 265-267 (2009).