A macrolide antibiotic
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Midecamycin A1

Item No. 46200

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
leucomycin V, 3,4B-dipropanoate
CAS Number
35457-80-8
Synonyms
  • NSC 154011
  • Platenomycin B1
  • SF837
  • YL-704 B1
Molecular Formula
C41H67NO15
Formula Weight
814.0
Purity
≥85%
Formulation (Request formulation change)
A solid
SMILES
O=C1C[C@@H](OC(CC)=O)[C@H](OC)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@@H]3O[C@@H](C)[C@H](OC(CC)=O)[C@](C)(O)C3)[C@H](N(C)C)[C@H]2O)[C@@H](CC=O)C[C@@H](C)[C@@H](O)/C=C\C=C\C[C@@H](C)O1
InChi Code
InChI=1S/C41H67NO15/c1-11-30(45)54-29-21-32(47)51-24(4)16-14-13-15-17-28(44)23(3)20-27(18-19-43)37(38(29)50-10)57-40-35(48)34(42(8)9)36(25(5)53-40)56-33-22-41(7,49)39(26(6)52-33)55-31(46)12-2/h13-15,17,19,23-29,33-40,44,48-49H,11-12,16,18,20-22H2,1-10H3/b14-13+,17-15-/t23-,24-,25-,26+,27+,28+,29-,33+,34-,35-,36-,37+,38+,39+,40+,41-/m1/s1
InChi Key
DMUAPQTXSSNEDD-DAITUVMSSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Cayman Chemical
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    Product Description

    Midecamycin A1 is a macrolide antibiotic and major component of midecamycin isolated from S. platensis malvinus.1,2,3 It is active against B. subtilis, M. phlei, and several antibiotic-sensitive or -resistant strains of S. aureus (MICs = 0.39, 12.5, and 0.39-3.125 µg/ml, respectively) except for erythromycin-resistant S. aureus (MIC = >25 µg/ml).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Tsuruoka, T., Shomura, T., Ezaki, N., et al. Studies on antibiotic SF-837, a new antibiotic. I. The producing microorganism and isolation and characterization of the antibiotic. J. Antibiot. (Tokyo) 24(7), 452-459 (1971).

    2. Hu, M., and Hu, C.-Q. Identification of the components of 16-membered macrolide antibiotics by LC/MS. Anal. Chim. Acta 535(1-2), 89-99 (2005).

    3. Kinumaki, A., Takamori, I., Sugawara, Y., et al. Studies on the macrolide antibiotic YL-704 complex. III. The structures of new macrolide antibiotics YL-704 A1 and B1. J. Antibot. (Tokyo) 27(2), 107-116 (1974).