A macrolide antibiotic
Related Products
Isomer(s)
28098Erythromycylamine
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Azathramycin

Item No. 46202

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one
CAS Number
76801-85-9
Synonyms
  • Azaerythromycin A
  • N-desmethyl Azithromycin
Molecular Formula
C37H70N2O12
Formula Weight
735.0
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Ethanol: Sparingly soluble: 1-10 mg/ml
SMILES
C[C@@H]1O[C@@H](O[C@@H]2[C@H](C(O[C@@H]([C@](C)([C@@H]([C@H](NC[C@@H](C[C@](C)([C@@H]([C@H]2C)O[C@@H]3O[C@@H](C[C@@H]([C@H]3O)N(C)C)C)O)C)C)O)O)CC)=O)C)C[C@@](C)(OC)[C@H]1O
InChi Code
InChI=1S/C37H70N2O12/c1-14-26-37(10,45)30(41)23(6)38-18-19(2)16-35(8,44)32(51-34-28(40)25(39(11)12)15-20(3)47-34)21(4)29(22(5)33(43)49-26)50-27-17-36(9,46-13)31(42)24(7)48-27/h19-32,34,38,40-42,44-45H,14-18H2,1-13H3/t19-,20-,21+,22-,23-,24+,25+,26-,27+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1
InChi Key
HRKNNHYKWGYTEN-HOQMJRDDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    50 mg

    $48

    Add

    100 mg

    $67

    Add

    250 mg

    $156

    Add
    Cayman Chemical
    Neutrophil Biology Wall Poster

    Explore how neutrophils shape the immune response in health and disease. This poster highlights neutrophil pathogen defense mechanisms, including phagocytosis, degranulation, and NETosis, as well as neutrophil roles in inflammation and NET-associated pathologies.

    DOWNLOAD NOW
    Product Description

    Azathramycin is a macrolide antibiotic.1 It is active against S. pyogenes, S. aureus, E. coli, and several strains of H. influenzae (MICs = ≤0.025, 0.78, 0.78, and 0.78-1.56 µg/ml, respectively). Azathramycin is also active against T. gondii (IC50 = 65 µM).2 Subcutaneous administration of azathramycin protects mice against an acutely fatal S. aureus infection with a half-maximal protective dose (PD50) value of 9 mg/kg.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bright, G.M., Nagel, A.A., Bordner, J., et al. Synthesis, in vitro and in vivo activity of novel 9-deoxo-9a-AZA-9a-homoerythromycin A derivatives; a new class of macrolide antibiotics, the azalides. J. Antibiot. 41(8), 1029-1047 (1988).

    2. Lee, Y., Choi, J.Y., Fu, H., et al. Chemistry and biology of macrolide antiparasitic agents. J. Med. Chem. 54(8), 2792-2804 (2011).