A nucleoside building block
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UDP-D-Galactosamine (sodium salt)

Item No. 46215

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
uridine 5′-(trihydrogen diphosphate), P′-(2-amino-2-deoxy-α-D-galactopyranosyl) ester, monosodium salt
Synonyms
  • UDP-GalN
Molecular Formula
C15H24N3O16P2 • Na
Formula Weight
587.3
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Water: Slightly soluble: 0.1-1 mg/ml
SMILES
O[C@H]([C@@H]1O)[C@H](N(C=CC2=O)C(N2)=O)O[C@@H]1CO[P](O[P](O[C@H]([C@@H]([C@H]3O)N)O[C@@H]([C@@H]3O)CO)([O-])=O)(O)=O.[Na+]
InChi Code
InChI=1S/C15H25N3O16P2.Na/c16-8-11(23)9(21)5(3-19)32-14(8)33-36(28,29)34-35(26,27)30-4-6-10(22)12(24)13(31-6)18-2-1-7(20)17-15(18)25;/h1-2,5-6,8-14,19,21-24H,3-4,16H2,(H,26,27)(H,28,29)(H,17,20,25);/q;+1/p-1/t5-,6-,8-,9+,10-,11-,12-,13-,14-;/m1./s1
InChi Key
LWXNAZWQTLSQKD-AMKQWFBQSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $79

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    5 mg

    $356

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    10 mg

    $632

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    Product Description

    UDP-D-galactosamine is a nucleoside building block that has been used in the synthesis of UDP-N-acetyl-α-D-galactosamine derivatives for the study of polypeptide N-acetylgalactosaminyltransferases (GalNAcTs).1 UDP-D-galactosamine accumulates in the liver of endotoxin-resistant and -sensitive strains of mice following administration of D-galactosamine (Item No. 22981).2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Choi, J., Wagner, L.J.S., Timmermans, S.B.P.E., et al. Engineering orthogonal polypeptide GalNAc-transferase and UDP-sugar pairs. J. Am. Chem. Soc. 141(34), 13442-13453 (2019).

    2. Freudenberg, M.A., Keppler, D., and Galanos, C. Requirement for lipopolysaccharide-responsive macrophages in galactosamine-induced sensitization to endotoxin. Infect. Immun. 51(3), 891-895 (1986).