A clickable form of pentadecanoic acid
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Unmodified Version(s)
17399Pentadecanoic Acid
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15-azido Pentadecanoic Acid

Item No. 46224

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
15-azido-pentadecanoic acid
CAS Number
118162-46-2
Synonyms
  • C15:0 Azide
  • FA 15:0 Azide
  • Azido-Palmitic Acid
  • Pentadecanoic Acid Azide
  • ω-azido Pentadecanoic Acid
Molecular Formula
C15H29N3O2
Formula Weight
283.4
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble: ≥ 10 mg/mlEthanol: Soluble: ≥ 10 mg/ml
SMILES
[N-]=[N+]=NCCCCCCCCCCCCCCC(O)=O
InChi Code
InChI=1S/C15H29N3O2/c16-18-17-14-12-10-8-6-4-2-1-3-5-7-9-11-13-15(19)20/h1-14H2,(H,19,20)
InChi Key
PYGQAGHMXCCROO-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    5 mg

    $45

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    10 mg

    $77

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    25 mg

    $158

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    50 mg

    $248

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    Product Description

    15-azido Pentadecanoic acid, also known as azido-palmitic acid, is a clickable form of pentadecanoic acid (Item No. 17399). It has been used in the study of glutathione peroxidase 4 (GPX4) palmitoylation in the context of ferroptosis in cancer cells and for metabolic labeling followed by conjugation to biotin-labeled reporters via copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted alkyne-azide cycloaddition (SPAAC) in vitro.1,2 15-azido Pentadecanoic acid has also been used in the synthesis of fluorescent probes for in vivo and ex vivo imaging of free fatty acid uptake in the heart and brown adipose tissue in mice.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Zhou, L., Lian, G., Zhou, T., et al. Palmitoylation of GPX4 via the targetable ZDHHC8 determines ferroptosis sensitivity and antitumor immunity. Nat. Cancer 6(5), 768-785 (2025).

    2. Zhang, Y., Li, J., Pei, X., et al. A SPAAC-based bioorthogonal method for verifying protein palmitoylation. Bio. Protoc. 16(18), e5835 (2026).

    3. Panagia, M., Yang, J., Gale, E., et al. A novel tracer for in vivo optical imaging of fatty acid metabolism in the heart and brown adipose tissue. Sci. Rep. 10(1), 11209 (2020).