A cell-permeable fluorogenic probe
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Cell Tracker Blue CMF2HC Dye

Item No. 46235

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-(chloromethyl)-6,8-difluoro-7-hydroxy-2H-1-benzopyran-2-one
CAS Number
215868-45-4
Synonyms
  • C12881
Molecular Formula
C10H5ClF2O3
Formula Weight
246.6
Purity
≥98%
Emission
464 nm
Excitation
371 nm
Formulation (Request formulation change)
A solid
λmax
326 nm
SMILES
ClCC(C1=C(O2)C(F)=C(O)C(F)=C1)=CC2=O
InChi Code
InChI=1S/C10H5ClF2O3/c11-3-4-1-7(14)16-10-5(4)2-6(12)9(15)8(10)13/h1-2,15H,3H2
InChi Key
QDLNIWVLVXWCPH-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $75

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    5 mg

    $225

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    10 mg

    $413

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    25 mg

    $938

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    Product Description

    Cell tracker blue CMF2HC dye is a cell-permeable fluorogenic probe.1,2 Upon reaction with intracellular thiols, it is retained by cells and displays an excitation/emission maxima of 371/464 nm, respectively.1,2,3 Cell tracker blue CMF2HC dye has been used to quantify intracellular glutathione (GSH) levels in vitro.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Yuan, P., Zhou, L., Zhang, X., et al. UCH-L1 inhibitor LDN-57444 hampers mouse oocyte maturation by regulating oxidative stress and mitochondrial function and reducing ERK1/2 expression. Biosci. Rep. 40(10), BSR20201308 (2020).

    2. Gugole, P.M., Zannoni, A., Forni, M., et al. Effects of holding and the addition of naloxone on vitrification of equine immature oocytes. Theriogenology 239, 117359 (2025).

    3. Dong, Y.-W., Qu, H.-X., Wang, Y.-Q., et al. Oleanolic acid improves the in vitro developmental competence of early porcine embryos by reducing oxidative stress and ameliorating mitochondrial function. Anim. Biosci. 38(3), 431-443 (2025).