An aminoglycoside antibiotic
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Ribostamycin (sulfate)

Item No. 46261

Technical Information
Formal Name
O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)-O-[β-D-ribofuranosyl-(1→5)]-2-deoxy-D-streptamine, suflate
CAS Number
53797-35-6
Molecular Formula
C17H34N4O10 • XH2SO4
Formula Weight
Purity
≥95%
A solid
SMILES
O=S(O)(O)=O.O[C@H]1[C@H](O[C@@H]2[C@H]([C@@H](C[C@@H]([C@H]2O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CN)O)O)N)N)N)O)O[C@H](CO)[C@H]1O
InChi Code
InChI=1S/C17H34N4O10.H2O4S/c18-2-6-10(24)12(26)8(21)16(28-6)30-14-5(20)1-4(19)9(23)15(14)31-17-13(27)11(25)7(3-22)29-17;1-5(2,3)4/h4-17,22-27H,1-3,18-21H2;(H2,1,2,3,4)/t4-,5+,6-,7-,8-,9+,10-,11-,12-,13-,14-,15-,16-,17+;/m1./s1
InChi Key
RTCDDYYZMGGHOE-YMSVYGIHSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Ribostamycin is an aminoglycoside antibiotic that has been found in S. ribosidificus.1,2 It is active against E. coli, S. epidermidis, and H. influenzae (MICs = 0.5-7.2 µM).2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hoshiko, S., Nojiri, C., Matsunaga, K., et al. Nucleotide sequence of the ribostamycin phosphotransferase gene and of its control region in Streptomyces ribosidificus. Gene 68(2), 285-296 (1988).

    2. Kong, J., Wu, Z.-X., Wei, L., et al. Exploration of antibiotic activity of aminoglycosides, in particular ribostamycin alone and in combination with ethylenediaminetetraacetic acid against pathogenic bacteria. Front. Microbiol. 11, 1718 (2020).