An anti-inflammatory agent
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Oxaceprol

Item No. 46278

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-acetyl-4R-hydroxy-L-proline
CAS Number
33996-33-7
Molecular Formula
C7H11NO4
Formula Weight
173.2
Purity
≥95%
Formulation (Request formulation change)
A solid
SMILES
O[C@H]1CN(C(C)=O)[C@H](C(O)=O)C1
InChi Code
InChI=1S/C7H11NO4/c1-4(9)8-3-5(10)2-6(8)7(11)12/h5-6,10H,2-3H2,1H3,(H,11,12)/t5-,6+/m1/s1
InChi Key
BAPRUDZDYCKSOQ-RITPCOANSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 g

    $25

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    10 g

    $38

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    25 g

    $69

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    Cayman Chemical
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    Product Description

    Oxaceprol is an anti-inflammatory agent.1,2 It does not decrease prostaglandin E2 (PGE2; Item No. 14010) or leukotriene C4 (LTC4; Item No. 20210) levels in isolated mouse peritoneal macrophages at 10 µM.2 Oxaceprol inhibits carrageenan-induced paw edema and yeast-induced hyperalgesia in rats and reduces synovial proliferation and pannus granulocyte infiltration in the knee joint in a rat model of adjuvant-induced arthritis.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Parnham, M.J. Antirheumatic agents and leukocyte pecruitment. Biochem. Pharmacol. 58(2), 209-215 (1999).

    2. Ionac, M., Parnham, M.J., Plauchithiu, M., et al. Oxaceprol, an atypical inhibitor of inflammation and joint damage. Pharmacol. Res. 33(6), 367-373 (1996).