A heterobifunctional linker molecule
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NH2-PEG4-(CH2)6-Cl (hydrochloride)

Item No. 46390

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
18-chloro-3,6,9,12-tetraoxaoctadecan-1-amine, monohydrochloride
CAS Number
1261238-20-3
Synonyms
  • Halo-PEG4-NH2
Molecular Formula
C14H30ClNO4 • HCl
Formula Weight
348.3
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Sparingly soluble: 1-10 mg/mlEthanol: Sparingly soluble: 1-10 mg/ml
SMILES
NCCOCCOCCOCCOCCCCCCCl.Cl
InChi Code
InChI=1S/C14H30ClNO4.ClH/c15-5-3-1-2-4-7-17-9-11-19-13-14-20-12-10-18-8-6-16;/h1-14,16H2;1H
InChi Key
XKHLDTNJZBRALN-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    100 mg

    $69

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    250 mg

    $155

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    500 mg

    $276

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    1 g

    $518

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    Product Description

    NH2-PEG4-(CH2)6-Cl is a heterobifunctional linker molecule.1 It has been used in the synthesis of fluorescent ligands for covalent labeling of modified bacterial haloalkane dehalogenase reporter or fusion proteins expressed in vitro, in vivo, or in fixed cells.1,2 NH2-PEG4-(CH2)6-Cl has also been used in the synthesis of chloroalkane-containing cereblon ligands.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kosaka, N., Ogawa, M., Choyke, P.L., et al. In vivo stable tumor-specific painting in various colors using dehalogenase-based protein-tag fluorescent ligands. Bioconjug. Chem. 20(7), 1367-1374 (2009).

    2. Du, D., Albert, L., Weitzel, M., et al. In situ construction of imidazopyridinium fluorescent labels for bioconjugation. Angew. Chem. Int. Ed. Engl. 65(21), e6231674 (2026).

    3. Steinebach, C., Sosič, I., Lindner, S., et al. A MedChem toolbox for cereblon-directed PROTACs. Medchemcomm 10(6), 1037-1041 (2019).