A synthetic intermediate
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4-Bromo-2-fluoro-N-methylbenzamide

Item No. 46398

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-bromo-2-fluoro-N-methyl-benzamide
CAS Number
749927-69-3
Synonyms
  • N-methyl 4-bromo-2-Fluorobenzamide
Molecular Formula
C8H7BrFNO
Formula Weight
232.1
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Sparingly soluble: 1-10 mg/ml
SMILES
O=C(C1=CC=C(Br)C=C1F)NC
InChi Code
InChI=1S/C8H7BrFNO/c1-11-8(12)6-3-2-5(9)4-7(6)10/h2-4H,1H3,(H,11,12)
InChi Key
BAJCFNRLEJHPTQ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

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    25 g

    $28

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    50 g

    $53

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    100 g

    $101

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    500 g

    $420

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    Product Description

    4-Bromo-2-fluoro-N-methylbenzamide is a synthetic intermediate that has been used in the synthesis of the androgen receptor antagonists enzalutamide (Item No. 11596) and apalutamide (ARN-509; Item No. 17132).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Xu, P., Zhu, L., Zhang, D., et al. Design and synthesis of fluorine aromatic scaffolds containing drugs approved by the US FDA from 2002 to 2022. Results Chem. 7, 101446 (2024).