An antiviral agent
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GRP-60367 (hydrochloride)

Item No. 46465

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(4-((2-(2,5-dimethylphenoxy)ethyl)amino)piperidin-1-yl)(pyridin-4-yl)methanone, dihydrochloride
Molecular Formula
C21H27N3O2 • 2HCl
Formula Weight
426.4
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Sparingly soluble: 1-10 mg/ml
SMILES
O=C(N1CCC(CC1)NCCOC2=CC(C)=CC=C2C)C3=CC=NC=C3.Cl.Cl
InChi Code
InChI=1S/C21H27N3O2.2ClH/c1-16-3-4-17(2)20(15-16)26-14-11-23-19-7-12-24(13-8-19)21(25)18-5-9-22-10-6-18;;/h3-6,9-10,15,19,23H,7-8,11-14H2,1-2H3;2*1H
InChi Key
ULEXKYQIHKYPCM-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    5 mg

    $119

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    10 mg

    $179

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    50 mg

    $536

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    100 mg

    $952

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    Cayman Chemical
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    Product Description

    GRP-60367 is an antiviral agent.1 It inhibits viral replication of rabies virus in BEAS-2B, HEp-2, and HEK293T cells (EC50s = 3, 2, and 52 nM, respectively). It selectively reduces viral titers in Neuro2a cells infected by rabies virus expressing its native glycoprotein but not by rabies virus expressing vesicular stomatitis virus (VSV) glycoprotein.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Du Pont, V., Wirblich, C., Yoon, J.J., et al. Identification and characterization of a small-molecule rabies virus entry inhibitor. J. Virol. 94(13), e00321-e00420 (2020).